MULTIPLICATION OF VARIOLA AND VACCINIA VIRUSES IN L CELLS
نویسندگان
چکیده
منابع مشابه
Growth of vaccinia and variola viruses in the one-day-old fertile hen's egg.
The cultivation of viruses in fertile hen's eggs has been widely utilized, providing many advantages for virological studies, since the pioneering work of Woodruff and Goodpasture (1931). In most of such works, however, eggs more than 5 days old have been used. Recently, Yoshino (1956) described a technique for experimental infection of the 1-day-old egg, revealing that such an early embryo sup...
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Smallpox was eradicated more than 10 years ago, but infection with another Orthopoxvirus, monkeypox virus, can result in a clinical picture resembling smallpox. Human infection with monkeypox virus is extremely rare, not easily transmitted, and confined to the rain forest belt of Africa (Z. Jezek and F. Fenner, p. 81-102, in Human Monkeypox, 1988). Evidence that variola virus, the causative age...
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CD8(+) T lymphocytes have been shown to be involved in controlling poxvirus infection, but no protective cytotoxic T-lymphocyte (CTL) epitopes are defined for variola virus, the causative agent of smallpox, or for vaccinia virus. Of several peptides in vaccinia virus predicted to bind HLA-A2.1, three, VETFsm(498-506), A26L(6-14), and HRP2(74-82), were found to bind HLA-A2.1. Splenocytes from HL...
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The isolation of presumptive hybrids from the viruses of variola major and cowpox has already been described (Dumbell & Bedson, 1964). We report here the detailed characterization of the 16 clones of virus obtained. As with the alastrimrabbit pox hybrids considered in the previous paper (Bedson & Dumbell, 1964), attention has been paid to the behaviour of the ceiling temperature character in re...
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Although the World Health Organization (WHO) declared global smallpox eradicated in 1980, concerns over emergent poxvirus infections have increased. Most poxvirus infections are zoonotic; exploring their genetic diversity will illuminate the genetic and evolutionary aspects of poxvirus infections, ecology, and epidemiology. In recent decades, several strains of the orthopoxvirus vaccinia virus ...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1959
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.78.2.290-291.1959